Turning the Tide – Help for Chronic Lyme Disease

Turning the Tide - Help for Chronic Lyme Disease

Now that science has accepted Borrelia has “persister” forms of bacteria that are resistant to antibiotics, there is new support for finding a cure to the chronic form of Lyme disease.John Hopkins was the first to openly publish their work on chronic Lyme but did so with carefully worded language. Other studies have followed – in particular the most recent Stanford study which refers to chronic Lyme openly – and both studies focus on treatment with combinations of antibiotics.

Now Northeastern has also published, and joined the ranks of cutting-edge microbiology labs dedicated to finding a cure for chronic Lyme disease.

The head of Northeastern’s Lyme disease research team is Uni­ver­sity Dis­tin­guished Pro­fessor Kim Lewis, who says the following:

“If Lyme is caught early, patients gen­er­ally recover quickly when treated with antibi­otics, pri­marily doxy­cy­line. How­ever, 10 to 20 per­cent of patients go on to develop a debil­i­tating chronic con­di­tion called Post-​​Treatment Lyme Dis­ease Syn­drome, or PTLDS, with symp­toms that include extreme fatigue, arthritis, muscle pain, and cog­ni­tive difficulties.

I find it amazing that when you show up at the doctor’s office you are not told that there is a 10 to 20 per­cent chance that your life as you know it has ended,” says Lewis. “Nobody seems to be focusing on the next step: How to pre­vent the sub­se­quent rise of the chronic condition.”

Dr. Lewis is working hard to change all that. His team recently received a large grant to attack the problem, and they have four promising approaches:

  • a mouse study of a reg­imen that erad­i­cated the bac­terium in the test tube, set­ting the stage for human trials;
  • antibi­otic cock­tails using existing drugs
  • strate­gies to dis­cover new drugs that selec­tively target the Lyme bac­terium
  • ways to alter the com­po­si­tion of the microbiome—the com­mu­nity of microor­gan­isms inhab­iting the human body—to stop the autoim­mune reac­tions that char­ac­terize the disease

All four show exciting promise. The grant, Lewis says, “will give us the flex­i­bility to test our approaches in par­allel, which will save us an enor­mous amount of time.”

Read more at http://www.northeastern.edu/news/2016/03/researchers-investigate-four-promising-new-treatments-for-lyme-disease/

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2 Responses to Turning the Tide – Help for Chronic Lyme Disease

  1. Ruben Castillo says:

    Has anybody tried apitherapy to treat Lyme? it is done in Tijuana Mexico and is very effective. Got nothing to loose except Lyme.

    • Jenna Seaver says:

      Apitherapy, or bee venom therapy, is very unconventional but there are many proponents (most notably Dr. Klinghardt in the Seattle area). I am terribly allergic to bee venom so I have steered clear but I know many people who have tried it. Unfortunately I have not heard of many people who have actually been cured…please let us know if it works for you! Best of luck!

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